منابع مشابه
Linkage analysis of a large pedigree with hereditary sideroblastic anaemia.
A large pedigree showing a history of pyridoxine responsive X linked sideroblastic anaemia was screened with several polymorphic DNA markers from the X chromosome. Linkage analysis between each marker and disease status was performed, giving a maximum two point lod score of 3.64 at zero recombination with the microsatellite marker PGK1P1 at Xq11.2-12. Close linkage to PGK at Xq13.3, one of the ...
متن کاملPedNavigator: a pedigree drawing servlet for large and inbred populations
PedNavigator is a pedigree drawing application for large and complex pedigrees. It has been developed especially for genetic and epidemiological studies of isolated populations characterized by high inbreeding and multiple matrimonies. PedNavigator is written in Java and is intended as a server-side web application, allowing researchers to 'walk' through family ties by point-and-clicking on per...
متن کاملIn-depth pedigree analysis in a large Brazilian Nellore herd.
A large herd of Nellore cattle was evaluated using in-depth pedigree analyses. Taking into account the incomplete pedigree due to the use of multiple young sires for mating, the average inbreeding coefficient was calculated as 1.73% for the last generation, which was higher than the regular inbreeding coefficient (0.25%). The effective population size was estimated to be 114, 245, and 101 for t...
متن کاملA simple method to approximate gene content in large pedigree populations: application to the myostatin gene in dual-purpose Belgian Blue cattle.
Gene content is the number of copies of a particular allele in a genotype of an animal. Gene content can be used to study additive gene action of candidate gene. Usually genotype data are available only for a part of population and for the rest gene contents have to be calculated based on typed relatives. Methods to calculate expected gene content for animals on large complex pedigrees are rela...
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ژورنال
عنوان ژورنال: The Japanese Journal of Genetics
سال: 1942
ISSN: 0021-504X,1880-5787
DOI: 10.1266/jjg.18.98